Every month I try to read an open-access article. After reading the article, I share the tittle and associated link with my followers. This is to encourage clinicians to read articles, stay up to date, and continue to grow.
This month I found a great piece to share with you. This one falls under asthma and biologic treatments. The objective of this paper is to “ [describe] the effects of alarmins and [discuss] the potential role of anti-alarmins in the context of existing biologics “ (p1 ).
Anti-alarmins in asthma: targeting the airway epithelium with next-generation biologics
By: C. M. Porsbjerg, A. Sverrild, C. M. Lloyd, A. N. Menzies-Gow and E. H. Bel
European Respiratory Journal 2020 56: 2000260; DOI: 10.1183/13993003.00260-2020
Link to the article: https://erj.ersjournals.com/content/56/5/2000260
Reasons you may find this article interesting
- Great review of inflammatory pathways in asthma (beginning on page 2).
- An in-depth discussion of targeting the alarmins using biological therapies (beginning on page 6).
- Useful visualization to help put things in perspective ( Figure 1 on page 3 and Figure 2 on page 7).
While I recommend you check out this article, I need to give you a heads-up. If you are not as familiar with asthma inflammatory pathways, you may need to dedicate more time to this piece. Personally, I had to come back to it a few times.
Happy learning and reading!
January 1st, 2021
Link to the blog post: https://respiratory.blog/lets-read-an-article-a-month-january-2021